Description | Whole blood mRNA expression profiling of host molecular networks in neonatal sepsis. Subset of GSE25504 using platform GPL6947 |
Purpose | We aimed to identify the gene network and pathway biology associated with neonatal sepsis by determining genome-wide alterations in host RNA in infected infants |
Experimental Design | Samples were obtained from control and infected human neonates. |
Experimental Variables | Sepsis (2021 ICD-10-CM code* = A41) |
Methods | Raw scan data were background subtracted, VST transformed and subsequently robust spline normalised as performed by the lumi package of Bioconductor. Array probe features that had a present count in one or more samples were retained. |
Platform | Illumina HumanHT-12 v3 |
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