Whole blood mRNA expression profiling of host molecular networks in neonatal sepsis. Subset of GSE25504 using platform GPL6947

We aimed to identify the gene network and pathway biology associated with neonatal sepsis by determining genome-wide alterations in host RNA in infected infants

Samples were obtained from control and infected human neonates.

Sepsis (2021 ICD-10-CM code* = A41)

Raw scan data were background subtracted, VST transformed and subsequently robust spline normalised as performed by the lumi package of Bioconductor. Array probe features that had a present count in one or more samples were retained.