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SIDRA

GXB

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Description

Expression of Neutrophil-related genes in patients with early sepsis-induced ARDS - GSE66890

Purpose

Clinical study of critically ill patients with sepsis and sepsis-related ARDS with whole blood RNA collected within the first 24 hours of admissionGoal of the study was to determine whether biologically relevant genes were identified to be differentially expressed genes in patients with sepsis alone and sepsis with ARDS

Experimental Design

Prospective observational study, case cohort design

Experimental Variables

Sepsis (2021 ICD-10-CM code* = A41)

Acute respiratory distress syndrome due to sepsis (2021 ICD-10-CM code* = J80-A41)

Methods

CEL files were generated using AGCC 4.0.0.1567G. The values in the CEL files were then normalized with the RMA normalization method, using the Affymetrix Power Tools suite, version 1.12.0.

Platform Affymetrix HuGene 1.0 ST v1
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