Sample Set Annotation Tool: Microarray Analysis of Acute Lung Injury - GSE10474 [Sepsis, Acute respiratory distress syndrome due to sepsis (ARDS) or Acute Lung Injury (ALI)]

Study Design
Assay
Sample Info
Files
Info
Samples
Group Sets
Analysis

Purpose

The Acute Respiratory Distress Syndrome (ARDS)/Acute Lung Injury (ALI) was described 30 years ago, yet the interaction between specific sets of genes involved in this syndrome remains incompletely understood.

Hypothesis

Experimental Design

13 patients with ALI + sepsis and 21 patients with sepsis alone were recruited from the Medical Intensive Care Unit of the University of Pittsburgh Medical Center between February 2005 and June 2007. Whole blood was obtained from each patient within 48 hours of admission, and RNA was extracted for gene expression profiling, and comparison analysis.

Experimental Variables

Sepsis (2021 ICD-10-CM code* = A41)

Acute respiratory distress syndrome due to sepsis (2021 ICD-10-CM code* = J80-A41)

Controls

Methods

GCRMA

Additional Information

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE10474

Expected Samples:

34 Samples Loaded: 34

Species

Human (Homo sapiens)

Sample Source

Whole Blood

Disease

Sepsis, Acute respiratory distress syndrome due to sepsis

Treatment Protocol

Growth Protocol

Extraction Protocol

standard Affymetrix protocol

Storage Conditions

Sample Set Spreadsheet

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Samples Preview

Sample ID	!Sample Title	Grouping	plasma	Patient with Acute Lung Injury
GSM264753	ALI patient #1	Acute Lung Injury	TRUE	TRUE
GSM264987	ALI patient #5	Acute Lung Injury	TRUE	TRUE
GSM264988	ALI patient #4	Acute Lung Injury	TRUE	TRUE
GSM264989	ALI patient #6	Acute Lung Injury	TRUE	TRUE
GSM264990	ALI patient #7	Acute Lung Injury	TRUE	TRUE

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File
sampleset4000185_sampleannotations.csv Sample Set Spreadsheet
sampleset4000185_sampleannotations.csv Sample Set Spreadsheet

Samples Viewer / Editor

All fields are editable except the "Sample ID" column. To edit a cell, click within the cell. To edit a "date" cell, click on the calendar icon. To cancel an edit, press the ESC key.

Sample ID	!Sample Title	Grouping	Plasma	Patient with Acute Lung Injury	Patient with sepsis only
GSM264753	ALI patient #1	Acute Lung Injury	TRUE	TRUE
GSM264987	ALI patient #5	Acute Lung Injury	TRUE	TRUE
GSM264988	ALI patient #4	Acute Lung Injury	TRUE	TRUE
GSM264989	ALI patient #6	Acute Lung Injury	TRUE	TRUE
GSM264990	ALI patient #7	Acute Lung Injury	TRUE	TRUE
GSM264991	ALI patient #8	Acute Lung Injury	TRUE	TRUE
GSM264992	ALI patient #9	Acute Lung Injury	TRUE	TRUE
GSM264994	ALI patient #10	Acute Lung Injury	TRUE	TRUE
GSM264995	ALI patient #11	Acute Lung Injury	TRUE	TRUE
GSM264996	ALI patient #12	Acute Lung Injury	TRUE	TRUE
GSM264998	ALI patient #13	Acute Lung Injury	TRUE	TRUE
GSM265000	ALI patient #2	Acute Lung Injury	TRUE	TRUE
GSM265001	ALI patient #3	Acute Lung Injury	TRUE	TRUE
GSM265004	sepsis patient #1	Sepsis	TRUE		TRUE
GSM265006	sepsis patient #2	Sepsis	TRUE		TRUE
GSM265008	sepsis patient #3	Sepsis	TRUE		TRUE
GSM265009	sepsis patient #4	Sepsis	TRUE		TRUE
GSM265011	sepsis patient #5	Sepsis	TRUE		TRUE
GSM265014	sepsis patient #6	Sepsis	TRUE		TRUE
GSM265016	sepsis patient #7	Sepsis	TRUE		TRUE
GSM265018	sepsis patient #8	Sepsis	TRUE		TRUE
GSM265019	sepsis patient #9	Sepsis	TRUE		TRUE
GSM265021	sepsis patient #10	Sepsis	TRUE		TRUE
GSM265022	sepsis patient #11	Sepsis	TRUE		TRUE
GSM265023	sepsis patient #12	Sepsis	TRUE		TRUE
GSM265024	sepsis patient #13	Sepsis	TRUE		TRUE
GSM265026	sepsis patient #14	Sepsis	TRUE		TRUE
GSM265027	sepsis patient #15	Sepsis	TRUE		TRUE
GSM265028	sepsis patient #16	Sepsis	TRUE		TRUE
GSM265029	sepsis patient #17	Sepsis	TRUE		TRUE
GSM265030	sepsis patient #18	Sepsis	TRUE		TRUE
GSM265031	sepsis patient #19	Sepsis	TRUE		TRUE
GSM265032	sepsis patient #20	Sepsis	TRUE		TRUE
GSM265033	sepsis patient #21	Sepsis	TRUE		TRUE

Group Sets View in Gene Expression Browser

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Module Analysis

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SIDRA